High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4(+) and CD8(+) memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients
Description
CONCLUSIONS: These findings (i) support a crucial role of functional, poly-antigenic α-CCCs/SARS-CoV-2 cross-reactive memory CD4^(+) and CD8^(+) T cells, induced following previous CCCs seasonal exposures, in protection against subsequent severe
