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PubMed COVID-19 Clinical Care

1051 - 1060 of 49233 results found

SARS-CoV-2 M(pro) oligomerization as a potential target for therapy

Date
Saturday, April 06, 2024 - 4:00 AM
Description
The main protease (M^(pro)) of SARS-CoV-2 is critical in the virus's replication cycle, facilitating the maturation of polyproteins into functional units. Due to its conservation across taxa, M^(pro) is a promising target for broad-spectrum antiviral

Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021

Date
Saturday, April 06, 2024 - 4:00 AM
Description
BACKGROUND: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable