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PubMed COVID-19 Clinical Care

171 - 180 of 3867 results found

Prozone masks elevated SARS-CoV-2 antibody level measurements

Date
Thursday, March 28, 2024 - 4:00 AM
Description
We report a prozone effect in measurement of SARS-CoV-2 spike protein antibody levels from an antibody surveillance program. Briefly, the prozone effect occurs in immunoassays when excessively high antibody concentration disrupts the immune complex

Preclinical animal models to evaluate therapeutic antiviral antibodies

Date
Thursday, March 28, 2024 - 4:00 AM
Description
Despite the availability of effective preventative vaccines and potent small-molecule antiviral drugs, effective non-toxic prophylactic and therapeutic measures are still lacking for many viruses. The use of monoclonal and polyclonal antibodies in an