mRNA-LNP vaccine-induced CD8(+) T-cells protect mice from lethal SARS-CoV-2 infection in the absence of specific antibodies
Description
The role of CD8^(+) T-cells in SARS-CoV-2 pathogenesis or mRNA-LNP vaccine-induced protection from lethal COVID-19 is unclear. Using mouse-adapted SARS-CoV-2 virus (MA30) in C57BL/6 mice, we show that CD8^(+) T-cells are unnecessary for the intrinsic
